Home > Name List By 1 > 1-[2-[4-[(E)-1-(4-iodophenyl)-2-phenylbut-1-enyl]phenoxy]ethyl] pyrrolidine

CAS No 116057-75-1 , 1-[2-[4-[(E)-1-(4-iodophenyl)-2-phenylbut-1-enyl]phenoxy]ethyl]
pyrrolidine

  • Name: 1-[2-[4-[(E)-1-(4-iodophenyl)-2-phenylbut-1-enyl]phenoxy]ethyl]
    pyrrolidine
  • Synonyms: Pyrrolidino-4-iodotamoxifen; SB-223030; CB-7432; CB 7432; SB 223030;1-[2-[4-[(E)-1-(4-iodophenyl)-2-phenylbut-1-enyl]phenoxy]ethyl]
    pyrrolidine;Iodoxifene; 116057-75-1;
  • CAS Registry Number:
  • Flash Point: 300.6°C
  • Boiling Point: 573.4°Cat760mmHg
  • Density: 1.329g/cm3
  • Refractive index: 1.622
  • Flash Point: 300.6°C
  • Molecular Weight: 523.44837
  • InchiKey: JJKOTMDDZAJTGQ-DQSJHHFOSA-N
  • InChI: InChI=1S/C28H30INO/c1-2-27(22-8-4-3-5-9-22)28(23-10-14-25(29)15-11-23)
    24-12-16-26(17-13-24)31-21-20-30-18-6-7-19-30/h3-5,8-17H,2,6-7,18-21H2,
    1H3/b28-27-
  • Molecular Formula: C28H30INO
  • Molecular Structure:CAS No:116057-75-1 1-[2-[4-[(E)-1-(4-iodophenyl)-2-phenylbut-1-enyl]phenoxy]ethyl]<br />pyrrolidine
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116057-75-1 Idoxifene

  • Idoxifene
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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116057-75-1 Idoxifene

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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116057-75-1 Idoxifene

  • Idoxifene
  • United States Carbomer, Inc. [Manufacturer]
  • Tel: 858-552-0992/ (800) 239-7129
  • Fax: 858-552-0999
  • Address: PO Box 261026-1026
    San Diego, CA 92196 ,United States
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116057-75-1 Idoxifene

  • Idoxifene, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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116057-75-1 Idoxifene

  • Idoxifene, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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116057-75-1 IDOXIFENE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China ,China
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References of 1-[2-[4-[(E)-1-(4-iodophenyl)-2-phenylbut-1-enyl]phenoxy]ethyl]
pyrrolidine
Title: Idoxifene
CAS Registry Number: 116057-75-1
CAS Name: 1-[2-[4-[(1E)-1-(4-Iodophenyl)-2-phenyl-1-butenyl]phenoxy]ethyl]pyrrolidine
Synonyms: 1-[2-[p-[(E)-b-ethyl-a-(p-iodophenyl)styryl]phenoxy]ethyl]pyrrolidine
Manufacturers' Codes: CB-7432
Molecular Formula: C28H30INO
Molecular Weight: 523.45
Percent Composition: C 64.25%, H 5.78%, I 24.24%, N 2.68%, O 3.06%
Literature References: Nonsteroidal estrogen antagonist; structurally analogous to tamoxifen, q.v. Prepn: R. McCague, EP 260066; idem, US 4839155 (1988, 1989 both to Nat. Res. Dev. Corp.); and structural activity: R. McCague et al., J. Med. Chem. 32, 2527 (1989). Stereochemistry: C. M. Nunn, E. J. Parker, Acta Crystallogr. C50, 2043 (1994). Modulating effects on multidrug resistance: J. Kirk et al., Biochem. Pharmacol. 48, 277 (1994); S. Y. Sharp et al., Br. J. Cancer 70, 409 (1994). Clinical evaluation in breast cancer: R. C. Coombes et al., Cancer Res. 55, 1070 (1995).
Properties: Crystals from light petroleum (pet. ether), mp 108-109° (McCague et al.); also reported as colorless monoclinic prisms from methanol (Nunn).
Melting point: mp 108-109° (McCague et al.)
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic (Hormonal); Antiestrogens; Selective Estrogen Receptor Modulator (SERM).