Home > Name List By b > Bleomycin sulfate

CAS No 9041-93-4 , Bleomycin sulfate

  • Name: Bleomycin sulfate
  • Synonyms: 3-[[2-[2-[2-[2-[4-[2-[6-Amino-2-[1-(2-amino-2-carbamoyl-ethyl)amino-2-carbamoyl-ethyl]-5-methyl-pyrimidin-4-yl]carbonylamino-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-3-(3H-imidazol-4-yl)propanoyl]amino-3-hydroxy-2-methyl-pentanoyl]amino-3-hydroxy-butanoyl]aminoethyl]-1,3-thiazol-4-yl]-1,3-thiazol-4-yl]carbonylamino]propyl-dimethyl-sulfonium hydrogen sulfate;bleomycin sulfate from streptomyces verticillus;Bleomycin sulfate;
  • CAS Registry Number:
  • Melting Point: 197 deg C (dec)
  • Water Solubility: 20 mg/mL in water
  • Safety Statements: 53-36/37-45-36-26
  • Hazard Symbols: T: Toxic;Xi: Irritant;
  • EINECS: 232-925-2
  • Molecular Weight: 1512.62
  • InChI: InChI=1/C55H83N17O21S3.H2O4S/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6;1-5(2,3)4/h14,17-19,21-25,29-30,34-43,53-54,64,73-75,77-81H,7-13,15-16,56H2,1-6H3,(H13-,57,58,59,60,61,62,63,65,66,69,70,71,72,76,82,83,84,85,86,87,88);(H2,1,2,3,4)/t21?,22?,23?,24?,25?,29-,30+,34?,35?,36?,37+,38+,39-,40-,41?,42-,43-,53+,54-;/m0./s1
  • Risk Statements: 46-40-36/37/38
  • Molecular Formula: C55H84N17O21S3.HSO4
  • Molecular Structure:CAS No:9041-93-4 Bleomycin sulfate
Search by region :

Select to

9041-93-4 Bleomycin sulfate

  • Bleomycin sulfate Synonyms:blenmycins;bleomycin,sulfate(salt);nsc-125066;bleomycin sulfate;bleomycin sulphate;bleomycin sulfate, streptomyces verticillus;blexane;bleo CAS:9041-93-4 MF:C110H168N34O46S7 MW:2927.17 EINECS:232-925-2 Chemical Properties:W...
  • Min. Order: 1000
  • FOB Price: USDfalse - false /
  • China Hubei Yuancheng Saichuang Technology Co.,Ltd. [Manufacturer]
  • Tel: 86-27-50756228
  • Fax: 86-27-88048077
  • Address: Wuchang wuhan,HubeiChina
Contact Supplier

9041-93-4 Bleomycin sulphate

  • Bleomycin sulphate
  • United States INDOFINE Chemical Co., Inc. [Manufacturer]
  • Tel: (908) 359-6778
  • Fax: (908) 359-1179
  • Address: 121 Stryker Lane
    Bldg 30, Suite 1
    Hillsborough, NJ 08844 ,United States
Contact Supplier

9041-93-4 Bleomycin sulfate

Contact Supplier

9041-93-4 Bleomycin sulphate

  • Bleomycin sulphate
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,China
Contact Supplier

9041-93-4 Bleomycine sulfate

  • Bleomycine sulfate, 99,00%
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,China
Contact Supplier

9041-93-4 Bleomycin sulfate

  • Bleomycin sulfate
  • China Betapharma Shanghai Inc.Co., Ltd [Manufacturer]
  • Tel: 86-21-62951620
  • Fax: 86-21-32230794
  • Address: Jinming Building 12A No. 8 Zunyi(S) Rd. Shanghai China 200336 shanghaiCHINA shanghai,China
Contact Supplier

9041-93-4 Bleomycin sulfate

  • Bleomycin sulfate, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
Contact Supplier

9041-93-4 Bleomycin Sulfate

  • China Trust&We Co., Ltd. [Manufacturer]
  • Tel: +86-21-61044582
  • Fax: +86-21-61044583
  • Address: 1-102,No.11,Dongjiaominxiang Alley,
    Dongcheng District,
    Beijing 100005,China ,China
Contact Supplier

9041-93-4 Bleomycin sulfate

  • Bleomycin sulfate, 99%UP
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
Contact Supplier

9041-93-4 Bleomycin sulfate

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China ,ZheJiangChina
Contact Supplier

Select to

References of Bleomycin sulfate
Title: Bleomycins
Manufacturers' Codes: NSC-125066
Literature References: A group of related glycopeptide antibiotics. Variations in the terminal amine account for differing activities. Isolated from Streptomyces verticillus: Umezawa, Antimicrob. Agents Chemother. 1965, 1079. Purification and separation into bleomycins A and B and their components: Umezawa et al., J. Antibiot. 19, 200, 210 (1966); T. Takita et al., ibid. 21, 79 (1968); 22, 237 (1969). Bleomycin A2 is the main component of the bleomycin employed clinically. Total structure elucidation: T. Takita et al., ibid. 25, 755 (1972). Revised structure: eidem, ibid. 31, 801 (1978). Terminal amines: Fujii et al., ibid. 26, 398 (1973). Synthesis of new bleomycins: T. Takita et al., ibid. 254. Total synthesis of bleomycin A2: eidem, Tetrahedron Lett. 23, 521 (1982). Improved total synthesis: S. Saito et al., J. Antibiot. 36, 92 (1983). Biosynthesis: Fujii et al., ibid. 27, 73 (1974). Bleomycins are believed to react with DNA and cause strand scission; they have also been shown to have a type of oxygen transferase activity. Mechanism of action studies: R. M. Burger et al., Life Sci. 28, 715 (1981); N. Marugesan et al., J. Biol. Chem. 257, 8600 (1982). Coordination chemistry: J. C. Dabrowiak, J. Inorg. Biochem. 13, 317 (1980). Clinical pharmacology: S. T. Crooke, Cancer Chemother. 3, 343 (1981). Characterization of analogs: N. J. Oppenheimer et al., J. Biol. Chem. 257, 1606 (1982). Reviews: H. Umezawa, Pure Appl. Chem. 28, 665-680 (1971); C. W. Haidle, R. S. Lloyd, Antibiotics vol. 5(pt. 2), F. E. Hahn, Ed. (Springer-Verlag, New York, 1979) pp 124-154; H. Umezawa, Anticancer Agents Based on Natural Product Models, J. M. Cassady, J. D. Douros, Eds. (Academic Press, New York, 1980) pp 147-166.
Properties: Colorless or yellowish powder which becomes bluish depending on Cu content. Very sol in water, methanol; slightly sol in ethanol. Practically insol in acetone, ethyl acetate, butyl acetate, ether. uv max: 244-248, 289-294 nm (E1%1cm 121-148, 102-121.5).
Absorption maximum: uv max: 244-248, 289-294 nm (E1%1cm 121-148, 102-121.5)
 
Derivative Type: Sulfate
CAS Registry Number: 9041-93-4
Trademarks: Blenoxane (BMS); Bleo (Nippon Kayaku)
 
Derivative Type: Bleomycin A2
CAS Registry Number: 11116-31-7
Synonyms: N1-[3-(Dimethylsulfonio)propyl]bleomycinamide
Molecular Formula: C55H84N17O21S3
Molecular Weight: 1415.55
Percent Composition: C 46.67%, H 5.98%, N 16.82%, O 23.74%, S 6.80%
 
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Antibiotics and Analogs.