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CAS No 95233-18-4 , 3-[4-(4-chlorophenyl)cyclohexyl]-4-hydroxynaphthalene-1,2-dione

  • Name: 3-[4-(4-chlorophenyl)cyclohexyl]-4-hydroxynaphthalene-1,2-dione
  • Synonyms: 95233-18-4; Acuvel; 566C;3-[4-(4-chlorophenyl)cyclohexyl]-4-hydroxynaphthalene-1,2-dione;Wellvone; Mepron (antipneumocystic); 566C80; Malarone Pediatric; Malarone; Mepron;
  • CAS Registry Number:
  • Density: 1.349g/cm3
  • Refractive index: 1.653
  • Molecular Weight: 366.83746
  • InchiKey: BSJMWHQBCZFXBR-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H19ClO3/c23-16-11-9-14(10-12-16)13-5-7-15(8-6-13)19-20(24)
    17-3-1-2-4-18(17)21(25)22(19)26/h1-4,9-13,15,24H,5-8H2
  • Molecular Formula: C22H19ClO3
  • Molecular Structure:CAS No:95233-18-4 3-[4-(4-chlorophenyl)cyclohexyl]-4-hydroxynaphthalene-1,2-dione
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95233-18-4 Atovaquone USP

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95233-18-4 Atovaquone

  • China Shanghai Sochem International Co., Ltd [Importer/Exporter]
  • Tel: +86-21-58317817
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95233-18-4 Atovaquone

  • China Inter-chemical.LTD [Manufacturers]
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  • Address: Renmin Nan Road Shenzhen,GuangdongChina
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95233-18-4 Atovaquone

  • China Kesheng Chemical Co.,LTD. [Manufacturers]
  • Tel: +86-519-83519908
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  • Address: 5# ,No 352, Hanjiang Road,Xinbei Area ,Changzhou,jiangsu,China. null,jiangsuChina
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95233-18-4 ATOVAQUONE

  • Canada Synth?se AptoChem Inc. [Manufacturer]
  • Tel: 514-496-4252
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  • Address: Synth?se AptoChem Inc.
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95233-18-4 Atovaquone

  • China Ganotolix biotechnology Co.,Ltd [Manufacturers]
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  • Address: No 118,qingzhou road,No 50,room 402,shanghai Shanghai,ShanghaiChina
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95233-18-4 Atovaquone

  • China Zhejiang Hisoar Pharm.Co., Ltd. [Manufacturers]
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  • Address: No.100 Waisha BranchRd. Jiaojiang Taizhou Zhejiang China Taizhou,ZhejianChina
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95233-18-4 Atovaquone

  • China TaiZhou Jinghao Chemical CO., Ltd. [Manufacturer]
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  • Address: Yantou Chemical Park, Taizhou, Zhejiang, China. Taizhou,ZhejiangChina
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95233-18-4 Atovaquone

  • China Hallochem Pharma Co.,Ltd. [Manufacturer]
  • Tel: +86-23-67030808-8820
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  • Address: Hallochem Pharma Co.,Ltd.
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    China null,nullChina
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95233-18-4 Atovaquone

  • China Beijing Intermediate Imp. & Exp. Co., Ltd. [Other]
  • Tel: +86-10-6345 3699
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  • Address: Suite 519, Huaheng Building, No. 31 South Binhe Street , Xuanwu District, Beijing 100055, P.R.China Beijing,BeijingChina
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References of 3-[4-(4-chlorophenyl)cyclohexyl]-4-hydroxynaphthalene-1,2-dione
Title: Atovaquone
CAS Registry Number: 95233-18-4
CAS Name: 2-[trans-4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthalenedione
Synonyms: trans-2-[4-(4-chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthoquinone
Manufacturers' Codes: 566C80; BW-566C; BW-566C-80
Trademarks: Mepron (GSK); Wellvone (GSK)
Molecular Formula: C22H19ClO3
Molecular Weight: 366.84
Percent Composition: C 72.03%, H 5.22%, Cl 9.66%, O 13.08%
Literature References: Hydroxynaphthoquinone derivative that inhibits mitochondrial electron transport. Prepn: A. T. Hudson, A. W. Randall, EP 123238; eidem, US 5053432 (1984, 1991 both to Burroughs Wellcome). Antiprotozoal activity, metabolism, and pharmacokinetics: A. T. Hudson et al., Drugs Exp. Clin. Res. 17, 427 (1991). Mechanism of action study: M. Fry, M. Pudney, Biochem. Pharmacol. 43, 1545 (1992). Clinical trial for prevention of pneumocystis pneumonia in AIDS patients: W. M. El-Sadr et al., N. Engl. J. Med. 339, 1889 (1998).
Properties: Crystals from acetonitrile, mp 216-219°. Practically insol in water.
Melting point: mp 216-219°
Therap-Cat: Antipneumocystic.
Keywords: Antipneumocystic.