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CAS No 95233-18-4 , 3-[4-(4-chlorophenyl)cyclohexyl]-4-hydroxynaphthalene-1,2-dione

  • Name: 3-[4-(4-chlorophenyl)cyclohexyl]-4-hydroxynaphthalene-1,2-dione
  • Synonyms: 95233-18-4; Acuvel; 566C;3-[4-(4-chlorophenyl)cyclohexyl]-4-hydroxynaphthalene-1,2-dione;Wellvone; Mepron (antipneumocystic); 566C80; Malarone Pediatric; Malarone; Mepron;
  • CAS Registry Number:
  • Density: 1.349g/cm3
  • Refractive index: 1.653
  • Molecular Weight: 366.83746
  • InchiKey: BSJMWHQBCZFXBR-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H19ClO3/c23-16-11-9-14(10-12-16)13-5-7-15(8-6-13)19-20(24)
    17-3-1-2-4-18(17)21(25)22(19)26/h1-4,9-13,15,24H,5-8H2
  • Molecular Formula: C22H19ClO3
  • Molecular Structure:CAS No:95233-18-4 3-[4-(4-chlorophenyl)cyclohexyl]-4-hydroxynaphthalene-1,2-dione
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95233-18-4 Atovaquone

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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95233-18-4 Atvaquone

  • Atvaquone
  • China PMIDA AGROCHEMICAL CO.,LTD [Manufacturer]
  • Tel: +86-023-67030808-8010
  • Fax: +86-023-67030809
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone401121 ChongqingCHINA Chongqing,China
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95233-18-4 Atovaquone

  • China Syntechem Co.,Ltd [Manufacturer]
  • Tel: +86-519-89882658
  • Fax: +86-519-8512 5369
  • Address: Syntechem Co.,Ltd
    18 South Zhulin Rd.
    Tianning district,Changzhou
    Jiangsu China 213022 ,China
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95233-18-4 Atovaquone

  • Atovaquone, 99,00%
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,China
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95233-18-4 Atovaquone

  • Atovaquone
  • China Betapharma Shanghai Inc.Co., Ltd [Manufacturer]
  • Tel: 86-21-62951620
  • Fax: 86-21-32230794
  • Address: Jinming Building 12A No. 8 Zunyi(S) Rd. Shanghai China 200336 shanghaiCHINA shanghai,China
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95233-18-4 Atovaquone

  • Atovaquone, 97%
  • China Suzhou Rovathin Foreign Trade Co.,Ltd [Manufacturer]
  • Tel: 86-512-65816829/ 86-512-61978430
  • Fax: 86-512-65816839
  • Address: Suzhou Rovathin Foreign Trade Co.,Ltd
    (Sales Company of Affiliated Plant in China)
    Room 603, 327 of ShiZi Street,
    Suzhou, Jiangsu, China 215006 ,China
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95233-18-4 Atovaquone

  • Atovaquone, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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95233-18-4 ATOVAQUONE ,99%

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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95233-18-4 Atovaquone

  • China Trust&We Co., Ltd. [Manufacturer]
  • Tel: +86-21-61044582
  • Fax: +86-21-61044583
  • Address: 1-102,No.11,Dongjiaominxiang Alley,
    Dongcheng District,
    Beijing 100005,China ,China
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95233-18-4 Atovaquone

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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References of 3-[4-(4-chlorophenyl)cyclohexyl]-4-hydroxynaphthalene-1,2-dione
Title: Atovaquone
CAS Registry Number: 95233-18-4
CAS Name: 2-[trans-4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthalenedione
Synonyms: trans-2-[4-(4-chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthoquinone
Manufacturers' Codes: 566C80; BW-566C; BW-566C-80
Trademarks: Mepron (GSK); Wellvone (GSK)
Molecular Formula: C22H19ClO3
Molecular Weight: 366.84
Percent Composition: C 72.03%, H 5.22%, Cl 9.66%, O 13.08%
Literature References: Hydroxynaphthoquinone derivative that inhibits mitochondrial electron transport. Prepn: A. T. Hudson, A. W. Randall, EP 123238; eidem, US 5053432 (1984, 1991 both to Burroughs Wellcome). Antiprotozoal activity, metabolism, and pharmacokinetics: A. T. Hudson et al., Drugs Exp. Clin. Res. 17, 427 (1991). Mechanism of action study: M. Fry, M. Pudney, Biochem. Pharmacol. 43, 1545 (1992). Clinical trial for prevention of pneumocystis pneumonia in AIDS patients: W. M. El-Sadr et al., N. Engl. J. Med. 339, 1889 (1998).
Properties: Crystals from acetonitrile, mp 216-219°. Practically insol in water.
Melting point: mp 216-219°
Therap-Cat: Antipneumocystic.
Keywords: Antipneumocystic.