Saracatinib

• Product NameSaracatinib
  CAS No.379231-04-6
  Purity>98%
  Min Quantity
  Price~
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  Molecular Structure

Detailed Description

SaracatinibSaracatinib (AZD0530) is a potent Src inhibitor with IC50 of 2.7 nM, and potent to c-Yes, Fyn, Lyn, Blk, Fgr and Lck; less active for Abl and EGFR (L858R and L861Q).

IC50 value: 2.7 nM(c-Src); 30 nM (v-Abl) [1]

Target: c-Src; v-Abl

in vitro: Saracatinib also potently inhibits other Src tyrosine kinase family members including c-Yes, Fyn, Lyn, Blk, Fgr, and Lck with IC50 from 4-10 nM.

Target:PKC

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