SB-431542

• Product NameSB-431542
  CAS No.301836-41-9
  Purity>98%
  Min Quantity
  Price~
• View Contact Detail

• 
  Molecular Structure

Detailed Description

SB-431542SB431542 is a potent and selective inhibitor of ALK5 with IC50 of 94 nM, 100-fold more selective for ALK5 than p38 MAPK and other kinases.

IC50 value: 94 nM [1]

Target: TGF-βReceptor

in vitro: SB 431542 inhibits the activin type I receptor ALK4 and the nodal type I receptor ALK7, which are responsible for the phosphorylation of Smad2.

Target:Estrogen Receptor_ERR

Product Links:http://www.medchemexpress.cn/sb-431542.html

Permanent link:http://www.medchemexpress.com/sb-431542.html