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ACY-1215

    Detailed Description

    ACY-1215Rocilinostat (ACY-1215) is a selective HDAC6 inhibitor with IC50 of 5 nM; >10-fold more selective for HDAC6 than HDAC1/2/3 (class I HDACs) with slight activity against HDAC8, minimal activity against HDAC4/5/7/9/11, Sirtuin1, and Sirtuin2.

    IC50 Value: 5 nM

    Target: HDAC6

    in vitro: ACY-1215 is a hydroxamic acid derivative.

    Target:Biochemical assay reagents

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