Tadalafil Citrate

• Product NameTadalafil Citrate
  CAS No.171596-29-5
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  Molecular Structure

Detailed Description

Detailed Product Description


Tadalafil / Cialis Sex Hormone For Men Sexual Function CAS 171596-29-5

Quick Detail:

Tadalafil is a PDE5 inhibitor marketed in pill form for treating erectile dysfunction (ED) under the name Cialis, and under the name Adcirca for the treatment of pulmonary arterial hypertension.


Description:

Tadalafil Citrate
Alias: Tadalafei;Cialis
CAS No: 171596-29-5
MF: C22H19N3O4
MW: 389.41
Purity: 99.5%
Appearance: white powder, odorless, tasteless, insoluble in water and alcohol.

Applications:


Although sildenafil (Viagra), vardenafil (Levitra), and tadalafil (Cialis) all work by inhibiting PDE5, tadalafil's pharmacologic distinction is its longer half-life (17.50 hours) - compared to sildenafil (4.0-5.0 hours) and vardenafil (4.0-5.0 hours) - resulting in longer duration of action, and so partly responsible for "The Weekend Pill" sobriquet. Furthermore, the longer half-life is the basis for current investigation of tadalafil's daily therapeutic use in relieving pulmonary arterial hypertension. Sildenafil is approved in several world regions as a thrice-daily therapy for pulmonary arterial hypertension.


Specifications:

Test Items Specification Test Results
Appearance White powder Conforms
Test method High pressure liquid chromatography(HPLC) Conforms
Melting Point 300℃～303℃ 301.5℃-302.6℃
Loss on drying ≤0.5% 0.24%
Heavy metals(Pb) ≤20ppm 7.5ppm
Residue on ignition ≤0.1% 0.08%
Relative substance ≤1.0% 0.145%
Assay (on dried basis) ≥98.5% 99.33%
Conclusion The product conform to USP 32.

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• Tadalafil Citrate