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GDC-0994

  • Purity: >98%
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

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Item specifics

  • Product Name.:GDC-0994
  • CAS No: 1453848-26-4

Details

GDC-0994GDC-0994 is highly selective for ERK1 and ERK2, with biochemical potency of 1.1 nM and 0.3 nM, respectively.

IC50 value: 1.1 nM/0.3 nM(ERK1/ERK2) [1]

Target: ERK1/ERK2 inhibitor

Daily, oral dosing of GDC-0994 results in significant single-agent activity in multiple in vivo cancer models, including KRAS-mutant and BRAF-mutant human xenograft tumors in mice.

Target:HIF

Product Links:http://www.medchemexpress.cn/gdc-0994.html

Permanent link:http://www.medchemexpress.com/GDC-0994.html

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