Current position:Home > Selling > GDC-0152

GDC-0152

  • Purity: >98%
  • Place of Orign: Princeton,New Jersey,United States
Ms.James Gao

Supplier Details

View the Seller's Store
Product Details
Company Profile

Item specifics

  • Product Name.:GDC-0152
  • CAS No: 873652-48-3

Details

GDC-0152GDC-0152 is a potent inhibitor of IAPs; binds to the XIAP BIR3 domain, the BIR domain of ML-IAP, and the BIR3 domains of cIAP1 and cIAP2 with K(i) values of 28, 14, 17, and 43 nM, respectively.

IC50 value: 28/14/17/43 nM(Ki, XIAP/ML-IAP/cIAP1/cIAP2) [1]

Target: IAPs inhibitor

in vitro:GDC-0152 can block protein?protein interactions that involve IAP proteins and pro-apoptotic molecules.

Target:PARP

Product Links:http://www.medchemexpress.cn/gdc-0152.html

Permanent link:http://www.medchemexpress.com/GDC-0152.html

Permanent link:

Company Related ProductsView the Seller's Products

GDC-0994

CAS No: 1453848-26-4

Purity: >98%

Min quantity: null null

Price: null ~ null null

Description: GDC-0994 GDC-0994 is highly selective for ERK1 and ERK2, with biochemical potency of 1.1 nM and 0.3 nM, respectively. IC50 value: 1.1 nM/0.3 nM(ERK1/ERK2) [1] Target: ERK1/ERK2 inhibitor Daily, oral dosing of GDC-0994 results in significant single-ag...

Detail more >>

GDC-0032

CAS No: 1282512-48-4

Purity: >98%

Min quantity: null null

Price: null ~ null null

Description: GDC-0032 GDC-0032 is a potent, next-generation β isoform-sparing PI3K inhibitor targeting PI3Kα/δ/γ with IC50 of 0.29 nM/0.12 nM/0.97nM, >10 fold selective over PI3Kβ. Target: DPP4 Product Links: http://www.medchemexpress.cn/gdc-0032.html Perman...

Detail more >>
Send message to this supplier

- Enter between 20 to 3,000 characters. English only.
Your message must be between 20-2000 characters.English only.

Look for similar items

  • Home > Organic Intermediates > Pharmaceutical Intermediates