Home > Name List By 2 > 2-[2-(2-chloro-6-fluoroanilino)-5-methylphenyl]acetic acid

CAS No 220991-20-8 , 2-[2-(2-chloro-6-fluoroanilino)-5-methylphenyl]acetic acid

  • Name: 2-[2-(2-chloro-6-fluoroanilino)-5-methylphenyl]acetic acid
  • Synonyms: Prexige; 220991-20-8; Lumiracoxib (USAN/INN);2-[2-(2-chloro-6-fluoroanilino)-5-methylphenyl]acetic acid; COX189; Prexige (Novartis); COX 189; COX-189; Joicela;
  • CAS Registry Number:
  • Density: 1.363 g/cm3
  • Refractive index: 1.628
  • Molecular Weight: 293.720623
  • InchiKey: KHPKQFYUPIUARC-UHFFFAOYSA-N
  • InChI: InChI=1S/C15H13ClFNO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12
    (15)17/h2-7,18H,8H2,1H3,(H,19,20)
  • Molecular Formula: C15H13ClFNO2
  • Molecular Structure:CAS No:220991-20-8 2-[2-(2-chloro-6-fluoroanilino)-5-methylphenyl]acetic acid
Search by region :

Select to

220991-20-8 Lumiracoxib

  • Lumiracoxib, 99,00%
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,China
Contact Supplier

220991-20-8 Lumiracoxib

  • Lumiracoxib
  • United States RIA International [Manufacturer]
  • Tel: 19735811282
  • Fax: 19735811283
  • Address: 11 Melanie Lane #17 East Hanover 07936 NJ UNITED STATES NJ,United States
Contact Supplier

220991-20-8 Lumiracoxib

  • Lumiracoxib, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
Contact Supplier

220991-20-8 LUMIRACOXIB

  • LUMIRACOXIB
  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
Contact Supplier

220991-20-8 Lumiracoxib

  • Lumiracoxib, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
Contact Supplier

220991-20-8 Lumiracoxib

  • India JAI RADHE SALES []
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. ,India
Contact Supplier

220991-20-8 Benzeneacetic acid,2-[(2-chloro-6-fluorophenyl)amino]-5-methyl-

  • China shanghai sphchem co.,ltd [Manufacturers]
  • Tel: +86-21-56491756 13512199871
  • Fax: 0
  • Address: NO.133, Wuye, Yangxin Road ,Shanghai China shanghai,shanghai ChinaChina
Contact Supplier

220991-20-8 Lumiracoxib

  • Lumiracoxib
  • China hangzhou Titan Chemical Co.,Ltd [Importer/Exporter]
  • Tel: 86 571 86838498
  • Fax: 86 571 86838499
  • Address: 32 Qingqun road, Hangzhou, Zhejiang, China Hangzhou,ZhejiangChina
Contact Supplier

220991-20-8 Benzeneacetic acid,2-[(2-chloro-6-fluorophenyl)amino]-5-methyl-

  • China Maple Chemical Co.,ltd. [Manufacturer]
  • Tel: 86-574- 87512300
  • Fax: 86-574-82095182
  • Address: No.347,Sanbei Road,Sanbei Town,Cixi ,Zhejiang,China Ningbo,ZhejiangChina
Contact Supplier

220991-20-8 Lumiracoxib

  • India Triveni Chemicals []
  • Tel: +91-(260)-2400022, 3258683
  • Fax: +91-(260)-2400022/3264008
  • Address: 135, Pancharatna, Char Rasta, G.I.D.C., Vapi, Gujarat 396 195, ,India
Contact Supplier

Select to

References of 2-[2-(2-chloro-6-fluoroanilino)-5-methylphenyl]acetic acid
Title: Lumiracoxib
CAS Registry Number: 220991-20-8
CAS Name: 2-[(2-Chloro-6-fluorophenyl)amino]-5-methylbenzeneacetic acid
Synonyms: 5-methyl-2-(2¢-chloro-6¢-fluoroanilino)phenylacetic acid
Manufacturers' Codes: COX-189
Trademarks: Prexige (Novartis)
Molecular Formula: C15H13ClFNO2
Molecular Weight: 293.72
Percent Composition: C 61.34%, H 4.46%, Cl 12.07%, F 6.47%, N 4.77%, O 10.89%
Literature References: Selective cyclooxygenase-2 (COX-2) inhibitor. Prepn: R. A. Fujimoto et al., WO 9911605; eidem, US 6310099 (1999, 2001 both to Novartis). Clinical evaluation of gastroduodenal tolerability: C. Rordorf et al., Aliment. Pharmacol. Ther. 18, 533 (2003). Clinical experience in dysmenorrhea: M. Bitner et al., Int. J. Clin. Pract. 58, 340 (2004); in rheumatoid arthritis: P. Geusens et al. ibid. 1033; in tension headache: E. Packman et al., Headache 45, 1163 (2005). Review of clinical pharmacology: C. M. Rordorf et al., Clin. Pharmacokinet. 44, 1247-1266 (2005); of clinical experience in osteoarthritis: F. Berenbaum et al., J. Int. Med. Res. 33, 21-41 (2005); in osteoarthritis, rheumatoid arthritis, and dental pain: T. J. Schnitzer et al., Curr. Med. Res. Opin. 21, 151-161 (2005).
Properties: mp 158-159°.
Melting point: mp 158-159°
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); Cyclooxygenase-2 Selective Inhibitor.