Home > Name List By 1 > 1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine

CAS No 298-57-7 , 1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine

  • Name: 1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine
  • Synonyms: Stugeron; Dimitronal; Mitronal; Marisan; Stutgin; Dimitron; Labyrin; Folcodal; Midronal;1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine;
  • CAS Registry Number:
  • Flash Point: 229.8°C
  • Boiling Point: 509.2°Cat760mmHg
  • Density: 1.093g/cm3
  • Refractive index: 1.649
  • Safety Statements: Poison by intravenous route. Moderately toxic by intraperitoneal route. Experimental reproductive effects. Human systemic effects by ingestion: allergic dermatitis. When heated to decomposition it emits toxic fumes of NOx.
  • Hazard Symbols: Xn
  • Flash Point: 229.8°C
  • EINECS: 206-064-8
  • Molecular Weight: 368.51392
  • InchiKey: DERZBLKQOCDDDZ-JLHYYAGUSA-N
  • InChI: InChI=1S/C26H28N2/c1-4-11-23(12-5-1)13-10-18-27-19-21-28(22-20-27)26(24-
    14-6-2-7-15-24)25-16-8-3-9-17-25/h1-17,26H,18-22H2/b13-10+
  • Risk Statements: 20/22-36/37/38-42/43
  • Molecular Formula: C26H28N2
  • Molecular Structure:CAS No:298-57-7 1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine
Search by region :

Select to

298-57-7 Stugeron

  • Basic Information Product Name: CINNARIZINE CAS: 298-57-7 ;16699-20-0 English Synonyms: CINNARIZINE,WHITE SOLID ; MIDRONAL ; CINNERAZINE ; APLACTAN ; STUGERON ; 1-BENZHYDRYL-4-((E)-3-PHENYL-ALLYL)-PIPERAZINE ; (E)-1-(DIPHENYLMETHYL)-4-(3-PHENYL PROP-...
  • Min. Order: 1000
  • FOB Price: USDfalse - false /
  • China Shanghai T&W Pharmaceutical Co., Ltd. [Manufacturer, Trading Company, Other]
  • Tel: 86-021-61551611
  • Address: 601, No. 1, 2277 Nong, Zu Chongzhi Road, Zhangjiang Hightech. Park, Pudong, Shanghai, China. shanghai,ShanghaiChina
Contact Supplier

298-57-7 CINNARIZINE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
Contact Supplier

298-57-7 Cinnarizine

  • China Chemrio International Limited [Manufacturer]
  • Tel: +86 574 2789 1268/ +86-139 5789 5864 (mobile)
  • Fax: +86 574 2789 1266
  • Address: Chemrio International Limited
    Room 611-612, Wante Business Center
    No.487 Yangmuqi Road,
    Hi-tech Park Ningbo, 315040,China ,China
Contact Supplier

298-57-7 Piperazine,1-(diphenylmethyl)-4-(3-phenyl-2-propen-1-yl)-

Contact Supplier

298-57-7 Piperazine,1-(diphenylmethyl)-4-(3-phenyl-2-propen-1-yl)-

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
Contact Supplier

298-57-7 Cinnarizine

  • China Trust&We Co., Ltd. [Manufacturer]
  • Tel: +86-21-61044582
  • Fax: +86-21-61044583
  • Address: 1-102,No.11,Dongjiaominxiang Alley,
    Dongcheng District,
    Beijing 100005,China ,China
Contact Supplier

298-57-7 Cinnarizine

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
Contact Supplier

298-57-7 Cinnarizine

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
Contact Supplier

298-57-7 Cinnarizine

  • China Ningbo Inno Pharmchem Co., Ltd. [Manufacturers]
  • Tel: +86-(574)-87319282
  • Fax: +86-(574)-56877908
  • Address: 5F, Building 4, 1035 Guangxian Rd., Ningbo Hi-Tech Park, Ningbo, Zhejiang 315040, Ningbo,ZhejiangChina
Contact Supplier

298-57-7 Cinnarizine

Contact Supplier

Select to

References of 1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine
Title: Cinnarizine
CAS Registry Number: 298-57-7
CAS Name: 1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine
Synonyms: 1-cinnamyl-4-diphenylmethylpiperazine; N-benzhydryl-N-trans-cinnamylpiperazine; 1-trans-cinnamyl-4-diphenylmethylpiperazine; 1-cinnamyl-4-benzhydrylpiperazine; 1-diphenylmethyl-4-trans-cinnamylpiperazine; cinnipirine
Manufacturers' Codes: 516-MD
Trademarks: Aplactan (Eisai); Aplexal (Taiyo); Apotomin (Kowa); Artate (Nippon Chemiphar); Carecin (Zensei Yakuhin); Cerebolan (Tobishi); Cerepar (Mepha); Cinaperazine (Yakult); Cinazyn (Italchimici); Cinnacet (Schwarzhaupt); Cinnageron (Streuli); Corathiem (Ohta); Denapol (Nagase); Dimitron; Eglen (Tatsumi); Folcodal (Syncro); Giganten (Troponwerke); Glanil (Janssen); Hilactan (Kyoritsu); Ixertol (Rottendorf); Katoseran (Hishiyama); Labyrin; Midronal (Delalande); Mitronal (Searle); Olamin (Sigamed); Processine (Sanko); Sedatromin (Takata); Sepan (Janssen); Siptazin (Isei); Spaderizine (Kotobuki); Stugeron (Janssen); Stutgeron (Janssen); Stutgin; Toliman (Corvi)
Molecular Formula: C26H28N2
Molecular Weight: 368.51
Percent Composition: C 84.74%, H 7.66%, N 7.60%
Literature References: Calcium channel blocker with anti-allergic and anti-vasoconstricting activity. Prepn: Janssen, US 2882271 (1959, Janssen). Pharmacology: Van Nueten, Janssen, Arch. Int. Pharmacodyn. Ther. 204, 37 (1973). Metabolism: Soudijn, van Wijngaarden, Life Sci. 7, 231 (1968). Clinical study in treatment of intermittent claudication: J. H. Barber et al., Pharmatherapeutica 2, 401 (1980). Assessment of calcium antagonist effects: M. Spedding, Arch. Pharmacol. 318, 234 (1982). HPLC determn in blood and plasma: M. Puttemans et al., J. Liq. Chromatogr. 7, 2237 (1984). Comparison of clinical pharmacokinetics with other antihistamines: D. M. Paton, D. R. Webster, Clin. Pharmacol. 10, 477-497 (1985).
 
Derivative Type: Hydrochloride
Molecular Formula: C26H28N2.HCl
Molecular Weight: 404.97
Percent Composition: C 77.11%, H 7.22%, N 6.92%, Cl 8.75%
Properties: mp 192° (dec). Soly in water: 2 mg/100 ml.
Melting point: mp 192° (dec)
 
Derivative Type: Mixture with vitamin B6
Trademarks: Emesazine
 
Therap-Cat: Antihistaminic. Vasodilator (peripheral, cerebral).
Keywords: Antihistaminic; Piperazines; Calcium Channel Blocker; Piperazine Derivatives; Vasodilator (Cerebral); Vasodilator (Peripheral).