Home > Name List By 4 > 4-methylsulfonyloxybutyl methanesulfonate

CAS No 55-98-1 , 4-methylsulfonyloxybutyl methanesulfonate

  • Name: 4-methylsulfonyloxybutyl methanesulfonate
  • Synonyms: Sulphabutin; Myeloleukon; Mielucin; Myelosan;Myleran;4-methylsulfonyloxybutyl methanesulfonate; Leucosulfan; Busulphan; Misulban; Mylecytan;
  • CAS Registry Number:
  • Transport: UN 2811 6.1/PG 1
  • Melting Point: 114-118 ºC
  • Density: 1.35 g/cm3
  • Safety Statements: R23/24/25;R36/37/38;R45;R46;R63
  • Hazard Symbols: T: Toxic;
  • EINECS: 200-250-2
  • Molecular Weight: 246.30176
  • InchiKey: COVZYZSDYWQREU-UHFFFAOYSA-N
  • InChI: InChI=1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3
  • Risk Statements: S28A;S36/37/39;S45;S53
  • Molecular Formula: C6H14O6S2
  • Molecular Structure:CAS No:55-98-1 4-methylsulfonyloxybutyl methanesulfonate

Related products

Search by region :

Select to

55-98-1 Busulfan

  • China China Langchem Inc. null
  • Tel: +86-(21)-58956006
  • Fax: +86-(21)-58956100
  • Address: 514 Room, 1# Building, 88# Cailun Road, Zhangjiang High Tech Park, Shanghai 201203, null,nullChina
Contact Supplier

55-98-1 Busulfan

Contact Supplier

55-98-1 BUSULFAN

  • United States Bromorganics Corporation [Manufacturer]
  • Tel: 847-238-9588
  • Fax: 847-238-9688
  • Address: Bromorganics Corporation
    P. O. Box 722
    Elk Grove Village, Illinois 60009 null,nullUnited States
Contact Supplier

55-98-1 Busulfan

  • India JAI RADHE SALES null
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. null,nullIndia
Contact Supplier

55-98-1 Busulfan

  • China Laiwu Hehui Chemical Co.,Ltd. null
  • Tel: +86-(531)-88772589
  • Fax: +86-(531)-88772589
  • Address: Huashan Rd., Jinan City, Shandong 250000, null,nullChina
Contact Supplier

55-98-1 Busulfan

  • India Manus Aktteva null
  • Tel: +91-(79)-65123395
  • Fax: +91-(79)-26463395
  • Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006, null,nullIndia
Contact Supplier

55-98-1 1,4-Butanediol dimethane sulfonate

  • 1,4-Butanediol dimethane sulfonate, 99%min
  • China Alway Chem, China [Manufacturer]
  • Tel: +86-532-8586-4000, 8586-5000
  • Fax: +86-532-8666-0350
  • Address: NO.51, TAIPING ROAD, QINGDAO, CHINA. 266001 null,SHANDONGChina
Contact Supplier

55-98-1 Busulfan, 99%

  • Busulfan, 99%
  • China Pleapharma Co.,Ltd [Manufacturer]
  • Tel: 86 23 67030808
  • Fax: 86 23 67030809
  • Address: 22F,Jingxin center,No.70 Xingguang Road,Yubei Zone,Chongqing402232 chongqingCHINA chongqing,nullChina
Contact Supplier

55-98-1 BUSULFAN

  • China Hainan Zhongxin Chemical Co., Ltd. [Manufacturer]
  • Tel: + 86 898 6854 0310/ + 86 21 64361616
  • Fax: + 86 898 6854 0119
  • Address: HAINAN COMPANY
    Address: Rm 811, Hainan Mandarin Hotel,
    Binhai Avenue, Haikou city,
    Hainan, P.R.China
    Tel: + 86 898 6854 0310
    Fax: + 86 898 6854 0119 null,nullChina
Contact Supplier

55-98-1 BUSULFAN

  • China HANGZHOU THINK CHEMICAL CO. [Manufacturer]
  • Tel: +86-571-81956191/ +86-571-81956192
  • Fax: +86-571-81956190
  • Address: 425 MOGAN HILL ROAD ,
    HANGZHOU, 310011 CHINA null,nullChina
Contact Supplier

Select to

3/7
Previous 1 2 3 4 5 6 7 Next
References of 4-methylsulfonyloxybutyl methanesulfonate
Title: Busulfan
CAS Registry Number: 55-98-1
CAS Name: 1,4-Butanediol dimethanesulfonate esters
Synonyms: 1,4-bis(methanesulfonoxy)butane; 1,4-di(methanesulfonyloxy)butane; 1,4-di(methylsulfonoxy)butane; methanesulfonic acid tetramethylene ester; tetramethylene bis(methanesulfonate); busulphan
Manufacturers' Codes: CB-2041; GT-41
Trademarks: Busulfex (Orphan Med.); Misulban (Nuovo ISM); Myleran (GSK)
Molecular Formula: C6H14O6S2
Molecular Weight: 246.30
Percent Composition: C 29.26%, H 5.73%, O 38.98%, S 26.04%
Line Formula: CH3SO2O(CH2)4OSO2CH3
Literature References: Alkylating agent with antileukemic activity. Discovery: A. Haddow, G. M. Timmis, Lancet 1, 207 (1953). Prepn: G. M. Timmis, US 2917432 (1959 to Burroughs Wellcome). Chemosterilant effect in boll weevils: J. W. Haynes et al., J. Econ. Entomol. 66, 619 (1973); J. W. Haynes, J. E. Wright, Southwest. Entomol. 7, 56 (1982). Pharmacokinetics: H. Ehrsson et al., Clin. Pharmacol. Ther. 34, 86 (1983). HPLC determn in human plasma: W. D. Henner et al., J. Chromatogr. 416, 426 (1987). Clinical pretreatment with cyclophosphamide, q.v., for bone marrow transplants: G. W. Santos et al., N. Engl. J. Med. 309, 1347 (1983). Comparative clinical trial with mitobronitol, q.v., in chronic myeloid leukemia: R. T. Silver et al., Cancer 60, 1442 (1987). Toxicity data: H. R. Scherf et al., Arzneim.-Forsch. 20, 1467 (1970). Review of pharmacology: C. D. R. Dunn, Exp. Hematol. 2, 101-117 (1974); of toxicology: J. B. Bishop, J. S. Wassom, Mutat. Res. 168, 15-45 (1986). Comprehensive description: M. Tariq, A. A. Al Badr, Anal. Profiles Drug Subs. 16, 53-83 (1987).
Properties: Crystals, mp 114-118°. Soly in acetone at 25°: 2.4 g/100 ml; in alcohol: 0.1 g/100 ml. Practically insol in water, but will dissolve slowly as hydrolysis takes place. LD50 i.v. in rats: 1.8 mg/kg (Scherf).
Melting point: mp 114-118°
Toxicity data: LD50 i.v. in rats: 1.8 mg/kg (Scherf)
CAUTION: This substance is listed as a known human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-39.
Use: Insect sterilant.
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Alkylating Agents; Alkyl Sulfonates.