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CAS No 768-94-5 , adamantan-1-amine

  • Name: adamantan-1-amine
  • Synonyms: 1-Aminoadamantane; 1-Adamantylamine; 768-94-5; adamantan-1-amine; Adamantylamine;1-Adamantanamine;adamantan-1-amine; Adamantanamine; Symmetrel;
  • CAS Registry Number:
  • Melting Point: 206-208 ºC
  • Density: 1.066 g/cm3
  • Refractive index: 1.557
  • Water Solubility: Soluble in organic solvents,insoluble in water.
  • Safety Statements: R22;R36/37/38
  • Hazard Symbols: Xi: Irritant;
  • EINECS: 212-201-2
  • Molecular Weight: 151.24868
  • InchiKey: DKNWSYNQZKUICI-UHFFFAOYSA-N
  • InChI: InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
  • Risk Statements: S26;S36
  • Molecular Formula: C10H17N
  • Molecular Structure:CAS No:768-94-5 adamantan-1-amine
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768-94-5 Amantadine

  • High quality and inexpensive efficient Medicine Amantadine with CAS768-94-5 1. Quick Detail Name: Amantadine Alias: 1-Adamantanamine(6CI,8CI); (Adamantan-1-yl)amine; 1-Adamantamine; 1-Adamantylamine; 1-Amantadine; 1-Aminoadamantane; Adamantamine; Ada...
  • Min. Order: 25
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  • China Wuhan Hezhong Bio-Chemical Manufacture Co. , Ltd [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 86-027-50755980
  • Fax: 86-027-88048077
  • Address: No.496,Zhongshan Road, Wuhan, Hubei, China Wuhan,HubeiChina
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768-94-5 amantadine

  • China Syntechem Co.,Ltd [Manufacturer]
  • Tel: +86-519-89882658
  • Fax: +86-519-8512 5369
  • Address: Syntechem Co.,Ltd
    18 South Zhulin Rd.
    Tianning district,Changzhou
    Jiangsu China 213022 ,China
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768-94-5 amantadine

  • China XinChem Corporation [Manufacturers]
  • Tel: +86-(21)-34123252
  • Fax: +86-(21)-54153973
  • Address: 102/30, 3455 Chunshen Road, Shanghai 201100, ,ShanghaiChina
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768-94-5 amantadine

  • China ORCHID CHEMICAL SUPPLIES LTD (OCS) [Importer/Exporter]
  • Tel: +86-571-85395792
  • Fax: +86-571-85420103
  • Address: 607, North Zhongshan Road, Hangzhou 310000 China ,ZhejiangChina
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768-94-5 1-AminoAdamantane

  • China Goly Chemical Co., Ltd. [Manufacturers]
  • Tel: +86-(632)-6163187
  • Fax: +86-(632)-5100028
  • Address: Room No.6.Building21 LongXingBeiLi,ShiZhong, ZaoZhua, ShanDong 277102, ZaoZhuang,ShanDongChina
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768-94-5 1-AMINOADAMANTANE

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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768-94-5 Amantadine Base

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768-94-5 Amantadine Base

  • India Manus Aktteva []
  • Tel: +91-(79)-65123395
  • Fax: +91-(79)-26463395
  • Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006, ,India
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768-94-5 Amantadine Base

  • China Betapharma(Shanghai)Co., Ltd. []
  • Tel: +86-(21)-33538380
  • Fax: +86-(21)-32082820
  • Address: No.17#-6D. 830 Lane, Maotai Road, Shanghai 200336, ,China
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768-94-5 Amantadine

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References of adamantan-1-amine
Title: Amantadine
CAS Registry Number: 768-94-5
CAS Name: Tricyclo[3.3.1.13,7]decan-1-amine
Synonyms: 1-adamantanamine; 1-aminoadamantane; 1-aminodiamantane (obsolete); 1-aminotricyclo[3.3.1.13,7]decane
Molecular Formula: C10H17N
Molecular Weight: 151.25
Percent Composition: C 79.41%, H 11.33%, N 9.26%
Literature References: NMDA-receptor antagonist; also active vs influenza A virus. Prepn: H. Stetter et al., Ber. 93, 226 (1960); W. Haaf, ibid. 97, 3234 (1964); P. Kovacic, P. D. Roskos, Tetrahedron Lett. 1968, 5833. Antiviral activity: W. L. Davies et al., Science 144, 862 (1964). GC determn in biological samples and pharmacodynamics: W. E. Bleidner et al., J. Pharmacol. Exp. Ther. 150, 484 (1965). Pharmacology and toxicology: V. G. Vernier et al., Toxicol. Appl. Pharmacol. 15, 642 (1969). Comprehensive description: J. Kirschbaum, Anal. Profiles Drug Subs. 12, 1-36 (1983). Review of use vs influenza A: R. L. Tominack, F. G. Hayden, Infect. Dis. Clin. North Am. 1, 459-478 (1987); of pharmacokinetics: F. Y. Aoki, D. S. Sitar, Clin. Pharmacokinet. 14, 35-51 (1988). Review of NMDA receptor binding and neuroprotective properties: J. Kornhuber et al., J. Neural Transm. 43, Suppl., 91-104 (1994). Series of articles on clinical experience in Parkinson's disease: ibid. 46, Suppl., 399-421 (1995).
Properties: Crystals by sublimation, mp 160-190° (closed tube) (Stetter). Also reported as mp 180-192° (Haaf). pKa: 10.1. Sparingly sol in water.
Melting point: mp 160-190° (closed tube) (Stetter); mp 180-192° (Haaf)
pKa: pKa: 10.1
 
Derivative Type: Hydrochloride
CAS Registry Number: 665-66-7
Manufacturers' Codes: EXP-105-1; NSC-83653
Trademarks: Adekin (Desitin); Lysovir (Alliance); Mantadan (Boehringer, Ing.); Mantadine (Endo); Mantadix (BMS); Symmetrel (Endo); Virofral (Novo)
Molecular Formula: C10H17N.HCl
Molecular Weight: 187.71
Percent Composition: C 63.99%, H 9.67%, N 7.46%, Cl 18.89%
Properties: Crystals from abs ethanol + anhydr ether, mp >360° (dec). Freely sol in water (at least 1:20); sol in alcohol, chloroform. Practically insol in ether. LD50 orally in mice, rats: 700, 1275 mg/kg (Vernier).
Melting point: mp >360° (dec)
Toxicity data: LD50 orally in mice, rats: 700, 1275 mg/kg (Vernier)
 
Derivative Type: Sulfate
CAS Registry Number: 31377-23-8
Trademarks: PK-Merz (Merz)
Molecular Formula: C10H17N.?H2SO4
Molecular Weight: 200.29
Percent Composition: C 59.97%, H 9.06%, N 6.99%, S 8.00%, O 15.98%
 
Therap-Cat: Antiviral; antiparkinsonian.
Keywords: Antidyskinetic; Antiparkinsonian; Antiviral.