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CAS No 77-86-1 , 2-amino-2-(hydroxymethyl)propane-1,3-diol

  • Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol
  • Synonyms: Tris buffer; Tris(Hydroxymethyl)aminomethane; Trisamine; Tromethane;2-amino-2-(hydroxymethyl)propane-1,3-diol; Trizma;Trometamol; Tris; Tham; 77-86-1;
  • CAS Registry Number:
  • Transport: 25kgs
  • Melting Point: 167-172 ºC
  • Boiling Point: 219-220 ºC (10 MMHG)
  • Density: 1,353 g/cm3
  • Refractive index: 1.531
  • Water Solubility: 550 G/L (25 ºC)
  • Safety Statements: R36/37/38
  • Hazard Symbols: Xi: Irritant;
  • HS Code: 29221980
  • EINECS: 201-064-4
  • Molecular Weight: 121.13504
  • InchiKey: LENZDBCJOHFCAS-UHFFFAOYSA-N
  • InChI: InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
  • Risk Statements: S26;S37/39
  • Molecular Formula: C4H11NO3
  • Molecular Structure:CAS No:77-86-1 2-amino-2-(hydroxymethyl)propane-1,3-diol
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77-86-1 Tris(hydroxymethyl)aminomethane

  • product name:Tris(hydroxymethyl)aminomethane; CAS NO.:77-86-1;
  • China Tocopharm Co.,Ltd. [Manufacturer, Other]
  • Tel: 86-021-31608287
  • Fax: 86-021-60919354
  • Address: RM506, No.80,Yichuan Rd.,Putuo District Shanghai,ShanghaiChina

77-86-1 Tris Base

  • Chemreagents is dedicated to bring high quality and cost effective chemical reagents and advanced intermediates to our global customers. Chemreagents has more than 30000 products in stock at our warehouse. In addition to the catalog products, Chemrea...
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  • United States Pure Chemistry Scientific Inc. [Manufacturer, Distributor/Wholesaler]
  • Tel: 1-857-9282050
  • Address: 108 Water Street, Room 4D Watertown,MAUnited States
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77-86-1 Tris Base

  • is an organic compound with the formula (HOCH2)3CNH2. It is extensively used in biochemistry and molecular biology.[1] In biochemistry, Tris is widely used as a component of buffer solutions, such as in TAE and TBE buffer, especially for solutions of...
  • Min. Order: 1000
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  • China Hunan Huateng Pharmaceutical Co. Ltd. [Manufacturer]
  • Tel: 86-0731-82251112
  • Address: Lugu Business Plaza E1, Yuelu District Changsha,HunanChina
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77-86-1 Tris(hydroxymethyl)aminomethane

  • Appearance: white crystalline powder MP / BP: 168-171 ℃ Content / Specifications: ≥99.5% Uses: Widely used in the preparation of buffer biochemistry and molecular biology experiments. In addition, Tris, or prepare an intermediate surface active age...
  • China Suzhou Yacoo science Corporation [Manufacturer]
  • Tel: 86-0512-87666785
  • Fax: 86-0512-87182056
  • Address: 17 Jinahi RD Suzhou Industrial Park China Suzhou,JiangsuChina
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  • 77-86-1 TRIS

    • "Appearance White crystal Assay 99.50%-101.0% Melting point 168°C-171°C Insolubles 0.03% max ASH 0.05% max Heavy metals 5ppm max Loss on drying 0.2% max PH 10.0-10.8 Color 5# Fe 1ppm max SO42+ 10ppm max Cl 3ppm max Abs (260nm,20%water) 0.1 max"
    • China Hangzhou Dingyan Chem Co.,Ltd [Manufacturer, Trading Company, Distributor/Wholesaler]
    • Tel: 86-571-88025800
    • Fax: 86-571-87156470
    • Address: Xiasha 571, 19TH Street E-COMMERCE 4A 601-602 , Jianggan Area hangzhou,ZhejiangChina

    77-86-1 Tris(hydroxymethyl)aminoethane

    • China ORCHID CHEMICAL SUPPLIES LTD (OCS) [Importer/Exporter]
    • Tel: +86-571-85395792
    • Fax: +86-571-85420103
    • Address: 607, North Zhongshan Road, Hangzhou 310000 China ,ZhejiangChina
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    77-86-1 Tris(hydroxymethyl)aminoethane

    • China YiPeng Chemical [Manufacturers]
    • Tel: 571 85376369
    • Fax: 571 88233092
    • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China ,ZheJiangChina
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    77-86-1 Tris(hydroxymethyl)aminoethane

    • Name:Tris(hydroxymethyl)aminoethane CAS:77-86-1 Synonyms:Tris MF:C4H11NO3 MW:121.14 Purity:≥99% Density:1.353 g/cm3 Melting Point:167-172 °C(lit.) Boiling Point:219-220 °C10 mm Hg(lit.) Flash Point:219-220°C/10mm Appearance:White crystalline or powd...
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    • China Wuhan Benjamin Pharmaceutical Chemical Co.Ltd [Manufacturer]
    • Tel: 86-27-50661279
    • Address: Room 1518 B Suite,Optical Valley Time Square, No 111 Guanshan Road, Hongshan District Wuhan,HubeiChina
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    77-86-1 Trometamol

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    77-86-1 Tris(hydroxymethyl)aminoethane

    • Hong kong ADVANCED TECH. & IND. CO., LTD. [Distributor/Wholesaler]
    • Tel: 86-23902293
    • Fax: 86-27898314
    • Address: UNIT B, 1/F, CHEONG SHING IND. BLDG., 17 WALNUT ST., TAI KOK TSUI, KLN, HONG KONG Hong Kong,nilHong kong
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    References of 2-amino-2-(hydroxymethyl)propane-1,3-diol
    Title: Tromethamine
    CAS Registry Number: 77-86-1
    CAS Name: 2-Amino-2-hydroxymethyl-1,3-propanediol
    Synonyms: trimethylol aminomethane; tris(hydroxymethyl)aminomethane; trisamine; tris buffer; trometamol; tromethane; TRIS
    Trademarks: THAM (Fisher Sci.); Trizma (Sigma-Aldrich)
    Molecular Formula: C4H11NO3
    Molecular Weight: 121.14
    Percent Composition: C 39.66%, H 9.15%, N 11.56%, O 39.62%
    Literature References: May be prepd by reduction or catalytic hydrogenation of the corresp nitro compd. Prepn of similar compds: Hass, Vanderbilt, US 2174242 (1940); Johnson, Degering, J. Org. Chem. 8, 7 (1943); Boileau, Mem. Poudres 35, Annexe 7-76 (1953). Prepn by electrolytic reduction: McMillan, US 2485982 (1949 to Comm. Solvents Corp.). Titrimetric standard: Whitehead, J. Chem. Educ. 36, 297 (1959). Monograph: Ann. N.Y. Acad. Sci. 92, Art. 2, pp 333-812 (June 17, 1961). Crystal structure: R. Rudman et al., Science 200, 531 (1978). GC determn in plasma: H. Hulshoff, H. B. Kostenbauder, J. Chromatogr. 145, 155 (1978). Pharmacokinetics in rabbits: H. Brasch, H. Iven, Arch. Int. Pharmacodyn. 254, 4 (1981). Use as a biological buffer: R. A. Durst, B. R. Staples, Clin. Chem. 18 206 (1972); S. P. Fling, D. S. Gregerson, Anal. Biochem. 155, 83 (1986); T. Higa, D. M. Desiderio, ibid. 173, 463 (1988). Interaction with hydroxyl radicals: M. Hicks, J. M. Gebicki, FEBS Lett. 199, 92 (1986). Review of clinical experience in treatment of acidemia: G. G. Nahas et al., Drugs 55, 191-224 (1998).
    Properties: Crystalline mass, mp 171-172°. bp10 219-220°. Weak, monoacidic base: pKb (25°): 5.91. pKa (20°): 8.3. pKa (37°): 7.82. pH of 0.1 molar aq soln 10.4. Aq solns do not absorb CO2 from the air. Soly at 25° (mg/ml) in water: 550; ethylene glycol: 79.1; methanol: 26; anhydr ethanol: 14.6; 95% ethanol: 22.0; DMF: 14; acetone: 2.0; ethyl acetate: 0.5; olive oil: 0.4; cyclohexane: 0.1; chloroform: 0.05; carbon tetrachloride: <0.05.
    Melting point: mp 171-172°
    Boiling point: bp10 219-220°
    pKa: pKb (25°): 5.91; pKa (20°): 8.3; pKa (37°): 7.82
    Use: In the synthesis of surface-active agents, vulcanization accelerators, pharmaceuticals. As emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, leather dressings, textile specialties, polishes, cleaning compds, so-called soluble oils. Absorbent for acidic gases. Biological buffer.
    Therap-Cat: Alkalinizing agent.
    Keywords: Alkalinizing Agent.