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CAS No 81147-92-4 , methyl 3-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propanoate

  • Name: methyl 3-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propanoate
  • Synonyms: 103598-03-4; AC1Q5ZXA; UNII-MDY902UXSR;(+-)-Esmolol;methyl 3-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propanoate; Esmolol (INN); CHEMBL768; AC1L1RWQ; CHEBI:4856; Esmolol [INN:BAN];
  • CAS Registry Number:
  • Melting Point: 48-50 ºC
  • Density: 1.026
  • Safety Statements: Experimental reproductive effects. When heated to decomposition it emits toxic vapors of NOx.
  • Hazard Symbols: A reproductive hazard.
  • Molecular Weight: 295.374
  • InchiKey: AQNDDEOPVVGCPG-UHFFFAOYSA-N
  • InChI: InChI=1S/C16H25NO4/c1-12(2)17-10-14(18)11-21-15-7-4-13(5-8-15)6-9-16(19)
    20-3/h4-5,7-8,12,14,17-18H,6,9-11H2,1-3H3
  • Molecular Formula: C16H25NO4
  • Molecular Structure:CAS No:81147-92-4 methyl 3-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propanoate
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81147-92-4 Benzenepropanoic acid,4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-, methyl ester

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81147-92-4; 103598-03-4 ESMOLOL

  • China HANGZHOU THINK CHEMICAL CO. [Manufacturer]
  • Tel: +86-571-81956191/ +86-571-81956192
  • Fax: +86-571-81956190
  • Address: 425 MOGAN HILL ROAD ,
    HANGZHOU, 310011 CHINA null,nullChina
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81147-92-4; 103598-03-4 ESMOLOL

  • China SINOCO CHEMICAL CO., LIMITED [Importer/Exporter]
  • Tel: +86-571-81956191, 81956192
  • Fax: 86-571-81956190 88386326
  • Address: 425 Ruiqi Mansion Moganshan Road , Hangzhou 310011 China. Hangzhou,ZhejiangChina
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81147-92-4; 103598-03-4 Esmolol

  • United Kingdom Fine Chem Trading LTD [Manufacturers]
  • Tel: +44-079-7062-7591
  • Fax: +44-087-0705-2950
  • Address: PO Box 292, Greenford, UB6 9ZL, England London,nullUnited Kingdom
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81147-92-4 ESMOLOL ACID

  • India VARDA Biotech (P) Ltd. [Manufacturer]
  • Tel: +91-22-6693 5686 / 2673 0141 / 2673 4258
  • Fax: +91-22-6693 5687
  • Address: 110 & 111, Kartik Complex
    New link Road, Andheri-(W)
    Mumbai-400053, INDIA. null,nullIndia
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81147-92-4; 103598-03-4 Esmolol

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81147-92-4 ESMOLOL

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81147-92-4; 103598-03-4 ESMOLOL

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81147-92-4; 103598-03-4 Esmolol

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81147-92-4 Benzenepropanoic acid,4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-, methyl ester

  • China Waykind Chemicals Corporation [Manufacturers]
  • Tel: +86-512-6238 8313
  • Fax: +86-512-6238 8313
  • Address: No.60,Yingfengjie, Ningwei, Xiaoshan,Hangzhou hangzhou,zhejiangChina
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References of methyl 3-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propanoate
Title: Esmolol
CAS Registry Number: 81147-92-4
CAS Name: 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzenepropanoic acid methyl ester
Synonyms: (±)-methyl 3-[4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]propionate; methyl p-[2-hydroxy-3-(isopropylamino)propoxy]hydrocinnamate
Molecular Formula: C16H25NO4
Molecular Weight: 295.37
Percent Composition: C 65.06%, H 8.53%, N 4.74%, O 21.67%
Literature References: Cardioselective b-adrenergic blocker. Prepn: E. I. Carlsson et al., EP 41491 (1982 to A.B. H?ssle), C.A. 96, 122391f (1982); P. W. Erhardt et al., EP 53435; eidem, US 4593119 (1982, 1986 both to Am. Hosp. Supply); P. W. Erhardt et al., J. Med. Chem. 25, 1408 (1982). Pharmacology: R. J. Gorczynski et al., J. Cardiovasc. Pharmacol. 5, 668 (1983); eidem, ibid. 6, 1548 (1984). Pharmacokinetics: A. Yacobi et al., J. Pharm. Sci. 72, 711 (1983). GC-MS determn in blood: C. Y. Sum, A. Yacobi, ibid. 73, 1177 (1984). Clinical studies of effect in supraventricular tachycardia: G. Klein et al., Int. J. Clin. Pharmacol. Ther. Toxicol. 22, 112 (1984); R. J. Gray et al., J. Am. Coll. Cardiol. 5, 1451 (1985). Symposium on pharmacology and clinical efficacy: Am. J. Cardiol. 56(11), 1F-62F (1985). Review of pharmacology and clinical efficacy: P. Benfield, E. M. Sorkin, Drugs 33, 392-412 (1987).
Properties: Oil, gradually forming crystalline rosettes at room temp, mp 48-50°.
Melting point: mp 48-50°
 
Derivative Type: Hydrochloride
CAS Registry Number: 81161-17-3
Manufacturers' Codes: ASL-8052
Trademarks: Brevibloc (Ohmeda)
Molecular Formula: C16H25NO4.HCl
Molecular Weight: 331.83
Percent Composition: C 57.91%, H 7.90%, N 4.22%, O 19.29%, Cl 10.68%
Properties: Crystals from methanol-ether, mp 85-86°.
Melting point: mp 85-86°
 
Therap-Cat: Antiarrhythmic.
Keywords: ?Adrenergic Blocker; Antiarrhythmic.